EML4-ALK kinase inhibitor 1

CAS No. 1373409-08-5

EML4-ALK kinase inhibitor 1 ( EML4 ALK kinase inhibitor 1 )

Catalog No. M26196 CAS No. 1373409-08-5

EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 335 Get Quote
10MG 500 Get Quote
25MG 806 Get Quote
50MG 1098 Get Quote
100MG 1485 Get Quote
500MG 2961 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    EML4-ALK kinase inhibitor 1
  • Note
    Research use only, not for human use.
  • Brief Description
    EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
  • Description
    EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
  • Synonyms
    EML4 ALK kinase inhibitor 1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Lp-PLA2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1373409-08-5
  • Formula Weight
    580.8
  • Molecular Formula
    C31H48N8O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1N[C@H]1CC[C@@H](CC1)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zehong Wan, et al. Bicyclic pyrimidone compounds. WO2013014185A1.
molnova catalog
related products
  • 7-Methylcoumarin

    7-Methylcoumarin with strong hepatoprotective activity.

  • Neobritannilactone B

    Neobritannilactone B has cytotoxic activity.

  • PIN1 inhibitor API-1

    PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM). PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development.